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Sapindus chinensis extract

Soapnut Extract

CAS: 223748-41-2

Molecular Formula:

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Sapindus chinensis extract - Names and Identifiers

Name Soapnut Extract
Synonyms Soapnut Extract
Sapindus Extract
Soapberry extract
Saprophytic extract
Sapindus mukorossi extract
Sapindus chinensis extract
SapindusMurkurossi Peel Extract
CAS 223748-41-2

Sapindus chinensis extract - References

Plant Source: seedless
plant extract Sapindus mukorossi Gaertn is a small deciduous tree belonging to the sapiaceae family, widely distributed in Southeast Asian countries, japan, China Taiwan and the area south of the Huaihe River, has a very wide range of use value, also known as the oil affected (Sichuan), fat beads (Jiangxi, Hunan, Guangdong), soap fruit (Mouth of Yunnan), bitter suffering trees (Hainan), sight waves (Taiwan), such as Ghost. The fruit of the seeds has important value, and the saponins and aglycones contained in the Peel have strong non-ionic surface activity, which is an excellent natural detergent, can be used to wash delicate fabrics such as silk and jewelry; In industry, can also be used to manufacture toothpaste, shampoo, soap, sterilization and pesticides; In addition, can also cough, phlegm, it also has a variety of biological activities, such as anti-microbial, anti-tumor, anti-platelet aggregation, anti-pain and anti-inflammatory. As a new raw material for the preparation of biodiesel, the kernel of saponines has high oil content. In addition, the tree shape is beautiful, the root system is developed, and it can absorb the harmful gases such as sulfur dioxide in the air and automobile exhaust. It has very important value in greening and soil and water conservation. Sapindus seed extract has a high value of multi-functional comprehensive utilization, and its research and utilization has attracted more and more attention of scientists at home and abroad.
FIG. 1 shows the absence of the Child
Chemical composition The main chemical composition of the extract was Sapindus saponin, the total content was about 5.33. Using high performance liquid chromatography-mass spectrometry (HPLC-MS) and electrospray ionization tandem mass spectrometry (ESI-MS/MS) to analyze the components in total saponins from Sapindus, the identification results mainly include: triterpenoid saponins and sesquiterpenoid saponins, among them, the triterpenoid saponins are mainly composed of pentacyclic triterpenoid saponins oleanolic acid type, tetracyclic triterpenoid saponins Euphorbia type and Dammarane type. SUN et al. isolated a new acyclic sesquiterpene from the pericarp of saponines. KUO et al. isolated five kinds of new Dammarane triterpenoid saponins from sapinmusaponins A- E from the fruit of the seeds, and found A, C, D, E is cytotoxic to human tumor cells. HUANG et al. isolated sapinmusaponins F-J five new euphoric triterpenoid saponins, K-N4 new Oleanolic triterpenoid saponins, o-P 2 kinds of new Dammarane type triterpenoid saponins, and found in pharmacological studies, 10 kinds of oleanolic acid type triterpenoid saponins with Ivy saponin as aglycone have cytotoxicity on Hela, WiDr, KB and other 6 kinds of human tumor cells. TENG et al. isolated two Euphorbia jacross-type triterpenoid saponins from the root of Sapindus, NI et al. Further isolated E-J6 new Euphorbia jacross-type triterpenoid saponins from sapimukosides. This information was compiled by Oriental editors.
pharmacological research 1, anti-tumor effect: Japanese scholar Chang weitun found that, the methanol solution of Sapindus seed extract has inhibitory effect on the proliferation of B16F10 (mouse melanoma), HeLa, MK-1 (human gastric cancer) cells, and the active part is concentrated in the single saponin component, the two-saponin component was completely inactive. HUANG et al.'s research also showed that the single saponin of the non affected fruit has cytotoxicity on some human tumor cells. 2, antihypertensive effect: Wang Weisheng et al. found that Sapindus saponin has antihypertensive effect on renal hypertensive rats, and can reduce vascular Nervousness peptide II, endothelin, and increase nitric oxide. Longzijiang and other studies have also shown that Sapindus saponins can reduce blood pressure in rats with essential hypertension, and its mechanism may be related to the changes of renin-vascular Nervousness peptide system and vascular endothelial function. 3, antibacterial effect: the British scholar TAMURA et al. studied the anti fungal activity and structure activity relationship of saponins in the peel of, it was found that the saponin mixture (including single-chain and double-chain glycosides, SP-mix) mixed with 70% and 85% methanol eluent had significant anti-dermatophytic effect, with the single-chain glycoside having stronger inhibitory effect. In addition, SP-mix had a strong inhibitory effect on yeast, in addition to the fungus in the fungus, the general fungi were ineffective; SP-mix had a moderate inhibitory effect on gram positive bacteria, Gram negative bacteria were ineffective. Fu Yong with Candida albicans experiments proved that the extract of 70% ethanol eluate also enriched the antibacterial active site. 4, anti-inflammatory effect: anti-ulcer MEYER and other experiments have proved that oral extract has anti-inflammatory and anti-ulcer effects. Meanwhile, it has been reported that ethanol extract of saponines has a significant inhibitory effect on Helicobacter pylori in vitro and in vivo, and does not produce drug resistance. 5, other pharmacological effects: Sapindus saponin also has liver protection, protection of myocardial ischemia, anti-thrombosis, spermicidal and other effects. Therefore, in the development and treatment of tumor, cardiovascular disease, skin disease, ulcer disease, and so on, the extract has great potential value.
market prospects Nippon is a new type of comprehensive resource with great development and utilization value, and its application value is very broad. However, due to the late start of the research work in our country, compared with foreign countries, the gap is large, still belongs to the initial stage, and needs further research and development and utilization. At present, there are some key problems to be solved in the development of Sapiens.
(1) to speed up the superior strain breeding and asexual rapid propagation technology research. With the improvement of the comprehensive development and utilization value of the extract from the seeds, the demand for the seeds is also increasing. At present, most of the seeds are directly planted by the seedlings cultivated by seed sowing, the results of poor performance, large individual differences, unstable traits, resulting in low yield, poor fruit quality, production efficiency is low, which restricts the development of disease-free industry. Therefore, the lack of high-quality and high-yield fruit-type seed seeds, supporting seedling asexual rapid propagation technology and high-yield and high-efficiency cultivation technology have become the technical bottleneck and technical problems to be solved in the development of seed extract industry. Therefore, to speed up the collection, evaluation and identification of the germplasm resources of the seed, the breeding of the seed and the research and promotion of the rapid propagation technology of the seed, it is the necessary technical support for the rapid and sustainable development of the seed extract industry.
(2) to strengthen the study of molecular biology of sapogenins at home and abroad, the research on sapogenins mainly focuses on Cultivation management, biology, saponin structure, the improvement of the extraction process of the components and the determination of the content of the effective components and the study of the functional aspects (pharmacological effects). Although the scientific community has a consensus on the basic framework and related enzymes in the process of saponin synthesis, there are few reports on the specific related genes of saponin synthesis. In the future, the biosynthesis pathway and possible Molecular regulation mechanism of triterpenoid saponins, which are the main components of the extract, should be further studied from the cloning and isolation of the key enzyme genes of the synthetic pathway of saponins in the fruit of the fruit. Many studies have pointed out that saponins can be antifungal, antimicrobial, allelopathic, etc. However, the molecular mechanism of resistance and toxicity behind it has not been fully elucidated and needs further study.
Last Update:2024-04-10 22:41:30
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CAS: 223748-41-2
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Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Soapnut Extract Visit Supplier Webpage Request for quotation
CAS: 223748-41-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
View History
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